In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman discuss the complexities of cancer with Dr. Joe Zundell, a cancer biologist. They explore the definition of cancer, its prevalence, and the hallmarks that characterize cancer cells. The conversation delves into the mechanisms of cancer growth, including sustaining proliferative signaling, evading growth suppression through the P53 gene, and the process of apoptosis. The discussion aims to make these complex topics accessible to a broader audience while highlighting the importance of understanding cancer biology. In this conversation, Dr. Joe Zundell discusses the complexities of cancer biology, focusing on key hallmarks such as immune response, replicative immortality, angiogenesis, and metastasis. He emphasizes the importance of early detection and the challenges of targeting cancer cells without affecting healthy cells. The discussion highlights the need for careful consideration of information regarding cancer treatment and the significance of working with healthcare professionals.

In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman welcome Dr. Namandjé Bumpus, Principal Deputy Commissioner of the FDA, who shares insights into the agency's operations and her path from academia to FDA leadership. The scientists explore the complexities of drug approval processes, the FDA's organizational structure, and its commitment to safety and transparency. Dr. Bumpus discusses the agency's efforts to advance health equity and adapt to emerging technologies, while addressing the critical challenge of maintaining public trust. This conversation offers listeners a unique glimpse into the inner workings of the FDA and its role in protecting public health.

In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman are joined by Dr. Ayesha Sherzai to explore brain health, with a focus on dementia and Alzheimer's disease. The scientists address common misconceptions and examine evidence-based approaches to cognitive health, including the role of nutrition, supplements, and music therapy. They debunk popular myths about brain usage and detoxification while emphasizing the importance of engaging in meaningful activities for cognitive resilience. Throughout the conversation, the experts highlight the intimate connection between brain health and overall well-being, providing listeners with reliable information to counter widespread misinformation in this field.

In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman discuss anxiety and panic disorders with clinical psychologist Dr. Nicole Lippman-Barile. The scientists explore the definitions of anxiety, its neurobiological underpinnings, and various types of anxiety disorders. They examine common myths surrounding nutrition and mental health, with a focus on the gut-brain connection. They conclude the episode by discussing effective coping mechanisms and treatment options for those struggling with anxiety disorders, providing listeners with valuable insights into managing these common mental health challenges.

In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman are joined by the leaders of the Human Immunome Project to explore groundbreaking research in immunology. The scientists discuss the project's mission to comprehensively map and understand the human immune system, emphasizing the importance of studying diverse populations through longitudinal research. They delve into the complexities of immune system dynamics, modern immunotherapy advances, and the development of predictive models for precision medicine. The conversation highlights how this ambitious collaborative effort integrates existing data while pioneering new methodologies, offering listeners insight into the future of personalized healthcare through innovative immune system research.