Animals in Research: An Enor-mouse Contribution

This week, we tackle a topic that people often avoid discussing….pre-clinical animal research.

We acknowledge the controversies surrounding animal research and that some feel very strongly about this subject. We discuss our personal experience conducting animal research and some applications of the research conducted. We cover several examples of biomedical advancements made possible thanks to animal research. We dig into the reasons for using animals in research as well as the limitations of non-human studies. Animals serve as “models” that represent certain aspects of a biological phenomenon to study. There are also times when certain animal models are used, like fish and frogs, whose anatomy and physiology may be quite different from humans, but still can help researchers address fundamental biological processes similar across species to develop knowledge to improve human health. We detail regulations and laws protecting animals used in biomedical research and protocols in place for these types of studies. We cover a couple high-profile cases of inhumane treatment of animal subjects which, we want to reiterate, is absolutely inexcusable. We wrap up the episode with a discussion of future directions and the national (and international) push to find alternatives to animal research. Make sure to tune in!

Check us out on Substack and Instagram:

www.theunbiasedscipod.substack.com

https://www.instagram.com/unbiasedscipod

Interested in advertising with us? Please reach out to advertising@airwavemedia.com, with “Unbiased Science” in the subject line.

PLEASE NOTE: The discussion and information provided in this podcast are for general educational, scientific, and informational purposes only and are not intended as, and should not be treated as, medical or other professional advice for any particular individual or individuals. Every person and medical issue is different, and diagnosis and treatment requires consideration of specific facts often unique to the individual. As such, the information contained in this podcast should not be used as a substitute for consultation with and/or treatment by a doctor or other medical professional. If you are experiencing any medical issue or have any medical concern, you should consult with a doctor or other medical professional.

Further, due to the inherent limitations of a podcast such as this as well as ongoing scientific developments, we do not guarantee the completeness or accuracy of the information or analysis provided in this podcast, although, of course we always endeavor to provide comprehensive information and analysis. In no event may Unbiased Science or any of the participants in this podcast be held liable to the listener or anyone else for any decision allegedly made or action allegedly taken or not taken allegedly in reliance on the discussion or information in this podcast or for any damages allegedly resulting from such reliance.

Learn more about your ad choices. Visit megaphone.fm/adchoices

Resources

• Celebrating the Discovery and Development of Insulin

• Researchers Discover Method in Mice to Restore Tamoxifen Sensitivity in Resistant Breast Cancer

• Dog with Duchenne Muscular Dystrophy Escapes the Disease, Spurring Interest in Potential New Treatment Approach

• Epilepsy Drug Discovered in Fish Model Shows Promise in Small Pediatric Clinical Trial

• Vaccine Protects Animals Against Anthrax and Plague

• Neurostimulation Technologies

• Comparative Oncology Program

• What Can Turtles and Other Tetrapods Tell Us About Longevity?

• Animal Testing and Research Is Highly Regulated

• Of Mice and Not Men: Differences Between Mouse and Human Immunology

• Of Mice, Dirty Mice, and Men: Using Mice to Understand Human Immunology

• Making Mouse Models That Reflect Human Immune Responses

• Precision Cancer Mouse Models Through Genome Editing with CRISPR-Cas9

• Limitations of Animal Studies for Predicting Toxicity in Clinical Trials

• Communicating About Animal Research with the Public

• Leading Breeder of Beagles for Research Slammed by Animal Welfare Inspectors

• In A First, State Bill Would Require Nearly Perfect Welfare Record for Research Dog and Cat Suppliers

• Research Animals Mistreated by Leading Supplier, Animal Welfare Group Alleges

• Dr. Oz’s Scientific Experiments Killed Over 300 Dogs, Entire Litter of Puppies

• Tissue Chip For Drug Screening

• REGENERATIVE MEDICINE INNOVATION PROJECT